You can color the textbox the normal tan
when the user finishes editing the recipe. In other words, add that 
code line to the textbox's Leave event, like this:
    Private
Sub txtInstructions_Leave(sender As
Object, e As
EventArgs) Handles
txtInstructions.Leave
        Dim
IndividualRecipe As XmlNode
        Dim
root As XmlNode
= doc.DocumentElement
        Dim
Titl As String
       
txtInstructions.BackColor = Color.FromArgb(255,
224, 192)
But you want to turn the textbox white
when the user starts editing the
recipe. You could do this in several events 
(KeyDown, Keypress, TextChanged events
like that). But remember they repeatedly execute every time the 
user types a character. The best solution
is to use the textbox's Enter
event—it works quite well.
Private
Sub txtInstructions_Enter(sender As
Object, e As
EventArgs) Handles
txtInstructions.Enter
       
txtInstructions.BackColor = Color.FromArgb(255,
255, 255)
End
Sub